Cih’s paper on inkjet printing of tumoroids with tumor-stroma interface is published on the Journal Materials Today Advances. In this work, Cih developed a new 3D printing method, named as “morphogenetic printing”, to rapidly produce tumoroids with extremely high cell density. Inkjet-printed morphogenesis of tumor-stroma interface using bi-cellular bioinks of collagen-poly(N-isopropyl acrylamide-co-methyl methacrylate) mixture Abstract …
Yingnan and Sameep’s paper to establish the mechanosensing mechanism of pain during injection of biologics is published in the Journal Extreme Mechanics Letters. In this paper, mechanical changes in the skin microenvironment are quantified in both experimentally and computationally, and correlated to potential pain signal. Experimental and computational analysis of the injection-induced mechanical changes in …
A collaborative paper by Yingnan with Yoon Yeo’s group is published in the Journal of Controlled Release. In this work, Yingnan reports precise control of diffusion and mixing processes on a microfludic platform to synthesize nanometer thick capsuled various hydrophobic drugs. A timescale-guided microfluidic synthesis of tannic acid-FeIIInetwork nanocapsules of hydrophobic drugs Yingnan Shen, Simseok A. Yuk, Soonbum Kwon, Hassan Tamam, Yoon Yeo, Bumsoo Han Abstract …
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Hye-ran’s paper on directed cell migration with Andrew Mugler’s group is published on the Journal Lab on a Chip. It is also selected as Lab on a Chip HOT Article 2023. In this work, Hye-ran proposed model migrating cancer cells as digital logic gates to process entangled chemical and fluidic microenvironmental cues. Cells function as …
A comprehensive review paper on computational models of drug transport by Sae Rome with Professor Ozcelikkale’s group at the Middle East Technical University is now published at the Journal Pharmaceutical Research. Predictive Design and Analysis of Drug Transport by Multiscale Computational Models Under Uncertainty Abstract Computational modeling of drug delivery is becoming an indispensable tool …
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Cih’s paper proposing a scaling law and dimensionless parameter for predictively printing particle-laden hydrogel is published in the International Journal of Heat and Mass Transfer. The paper provide a new guideline to print “digital” hydrogel. A scaling law of particle transport in inkjet-printed particle-laden polymeric drops Cih Cheng, Yoon Jae Moon, Jun Young Hwang, George …
Hye-ran’s paper collaboratively developed with Dr. Mugler’s group at the University of Pittsburgh is now published in Journal iScience. We studied the cells’ biophysical capacity to decipher complex chemical cues during migration. Signal processing capacity of the cellular sensory machinery regulates the accuracy of chemotaxis under complex cues Hye-ran Moon, Soutick Saha, Andrew Mugler, and …
Our recent paper on the Journal Lab on a Chip is highlighted as the Journal Cover article. The paper regards creation of functional pancreatic acinus model using reprogrammed cancer cells by PTF1a induction. The artwork is developed by Hye-ran.
Our paper developing a normal pancreatic acinus model is published in Lab on a Chip. In this paper, we reprogram pancreatic cancer cells to create cells with normal phenotypes. Engineering of a functional pancreatic acinus with reprogrammed cancer cells by induced PTF1a expression A pancreatic acinus is a functional unit of the exocrine pancreas producing digest enzymes. …
A collaborative paper with groups at Indiana University Medical School and Harvard Medical School is published in the Journal of Experimental & Clinical Cancer Research. This paper regards drug discovery for pancreatic cancer focusing on a protein called Ref-1. Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a …
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