Engineering of Biomaterials for Tumor Model

A review paper by Sae Rome regarding the engineering biomaterials for tumor modeling is now published at Materials Today Advances. This paper was written with Dr. Joon Kong’s Group at UIUC and Dr. Matt Flick’s Group and UNC. Engineering of biomaterials for tumor modeling Sae Rome Choi, Yi Yang, Kai-Yu Huang, Hyun Joon Kong, Matthew …

Pancreatic Cancer Model with Intra-Tumoral Heterogeneity

Our work on pancreatic cancer model with heterogenous cancer cell population is published in the Journal Lab on a Chip. An engineered pancreatic cancer model with intra-tumoral heterogeneity of driver mutations Hye-ran Moon, Altug Ozcelikkale, Yi Yang, Bennett D. Elzey, Stephen F. Konieczny and Bumsoo Han Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a complex disease …

Anuhya received Award at SURF Symposium

Anu received an Outstanding Researcher Award at 2020 Summer Undergraduate Research Fellowship Symposium. She has performed a computational research and presented her poster as below. Research Title: Effects of Cell-Cell Contact During Multicellular Migration  Graduate Mentor: Hye-Ran Moon PI: Dr. Bumsoo Han Department: School of Mechanical Engineering

Hye-ran Moon’s PhD Defense

Hye-ran successfully defended her Ph.D. defense via WebEx. She will stay at the group as a Postdoc. DIRECTED CELL MIGRATION INDUCED BY MULTIPLE CUES IN THE ENGINEERED MICROENVIRONMENT ABSTRACT Directed cancer cell migration induced by the environmental signals is a critical process in cancer metastasis. Cancer cells are exposed to complex chemical and mechanical signals …

Triple-Negative Breast Cancer Model

Our work on microfluidic tumor models of subtype-specific triple-negative breast cancer is published at the Journal PlosONE. Subtype-specific characterization of breast cancer invasion using a microfluidic tumor platformHye-ran Moon, Natalia Ospina-Muñoz, Victoria Noe-Kim, Yi Yang, Bennett D. Elzey, Stephen F. Konieczny, and Bumsoo Han AbstractUnderstanding progression of breast cancers to invasive ductal carcinoma (IDC) can …

Ann Steele’s Thesis Defense

Ann successfully finished her thesis defense through online final exam. Her thesis title is “Finite Element Mechanics Analysis of Growth and Invasion of Pancreatic Ductal Adenocarcinoma.” She will start her new research fellow position at GE Research Laboratory.  

High throughput histology of spheroids and organoids

Please note Purdue news release regarding our new platform to transfer spheroids & organoids from multi-well plates to a single histology cassette. This idea was initially developed by a contract from NCI and is recently funded by the Purdue Research Foundation for commercialization. We are developing this new collapsable basket array using 3D printing and …