Author: btp.lab@gmail.com
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Purdue Challenge 5k
Although it was cold, Sae Rome, Hye-ran, Jackson, Yingnan and Bumsoo ran the 5K this year!!!
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Scaling law for hydrogel printing
Cih’s paper proposing a scaling law and dimensionless parameter for predictively printing particle-laden hydrogel is published in the International Journal of Heat and Mass Transfer. The paper provide a new guideline to print “digital” hydrogel. A scaling law of particle transport in inkjet-printed particle-laden polymeric drops Cih Cheng, Yoon Jae Moon, Jun Young Hwang, George…
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Cell’s signal processing machinery
Hye-ran’s paper collaboratively developed with Dr. Mugler’s group at the University of Pittsburgh is now published in Journal iScience. We studied the cells’ biophysical capacity to decipher complex chemical cues during migration. Signal processing capacity of the cellular sensory machinery regulates the accuracy of chemotaxis under complex cues Hye-ran Moon, Soutick Saha, Andrew Mugler, and…
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Research Theme
Our research theme is “biotransport phenomana,” which are trasnport processes of matters, momentum, energy and even information through biological systems. We measure, model and understand these processes to engineer new biotechnology and biomaterials. Current research projects include drug and nanoparticle transport in the tumor microenvironment, biomimetic disease models of pancreatic cancer and blood-brain interface for…
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Cover of Lab on A Chip
Our recent paper on the Journal Lab on a Chip is highlighted as the Journal Cover article. Lab Chip, 2021,21, 3619-3619 The paper regards creation of functional pancreatic acinus model using reprogrammed cancer cells by PTF1a induction. The artwork is developed by Hye-ran.
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Pancreatic Acinus on Chip
Our paper developing a normal pancreatic acinus model is published in Lab on a Chip. In this paper, we reprogram pancreatic cancer cells to create cells with normal phenotypes. Engineering of a functional pancreatic acinus with reprogrammed cancer cells by induced PTF1a expression A pancreatic acinus is a functional unit of the exocrine pancreas producing digest enzymes.…
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Drug discovery for pancreatic cancer: Ref-1 redox activity
A collaborative paper with groups at Indiana University Medical School and Harvard Medical School is published in the Journal of Experimental & Clinical Cancer Research. This paper regards drug discovery for pancreatic cancer focusing on a protein called Ref-1. Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a…
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Jon Gilvey’s MS Defense and Commencement
Jon successfully defended his MS Thesis entitled “Effects of thrombin on the growth of pancreatic cancer cells and cancer associated fibroblasts using a microfluidic model.” He will continue his PhD study at Purdue.
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Jonathan Gilvey, MS
Jon completed his MS study in Mechanical Engineering May 2021. He is the recipient of the Arrasmith Fellowship of 2018. He received B.S. in Mechanical Engineering from Washington State University (2018).
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Tarun Singh, Ph.D (2025)
Tarun graduated with PhD in Mechanical Engineering in May 2025 from Purdue University. He received his M.T. and B.T. in Mechanical Engineering from Indian Institute of Technology, Varanasi.
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Engineering of Biomaterials for Tumor Model
A review paper by Sae Rome regarding the engineering biomaterials for tumor modeling is now published at Materials Today Advances. This paper was written with Dr. Joon Kong’s Group at UIUC and Dr. Matt Flick’s Group and UNC. Engineering of biomaterials for tumor modeling Sae Rome Choi, Yi Yang, Kai-Yu Huang, Hyun Joon Kong, Matthew…