Author: btp.lab@gmail.com
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Group migration of fibroblasts
Our work on massive migration of fibroblasts is published in the Journal of Royal Society Interface. Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices Altug Ozcelikkale, J. Craig Dutton, Frederick Grinnell, Bumsoo Han Abstract Fibroblast migration plays a key role during various physiological and pathological processes. Although migration of…
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ROS-responsive drug carrier
A collaborative paper with Professor Joon Kong’s group at UIUC is published at ASC Applied Materials & Interfaces. Active Antioxidizing Particles for On-Demand Pressure-Driven Molecular Release Yongbeom Seo, Jiayu Leong, Jye Yng Teo, Jennifer W. Mitchell, Martha U. Gillette, Bumsoo Han, Jonghwi Lee, and Hyunjoon Kong Abstract Overproduced reactive oxygen species (ROS) are closely…
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Altug Ozcelikkale, Ph.D., Postdoc Fellow
Altug completed his Ph.D. study in Mechanical Engineering at Purdue University (2015), and worked as a Postdoc Fellow (2017) in the Han Group. He moved to a Postdoc Fellow Position at the University of Maryland. Check his latest activities at his Linkedin Profile.
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Anuhya Edupuganti, Undergrad Student
Anuhya (Anu) graduated with B.S. in Mechanical Engineering Major at Purdue University in May 2022. She joined the Han Research Group in January 2020.
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Jessica Bendell, Undergraduate Student
Jessica is a undergraduate student with Biomedical Engineering Major. She joins the Han Research Group in August 2018.
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Samuel Schiavitti, Undergraduate Student
Sam graduated with B.S. in Mechanical Engineering at Purdue University in May 2022. He worked on design and manufacturing high throughput 3D cell culture platform by 3D printing.
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Jackson Williams, Undergraduate Student
Jackson is an Mechanical Engineering Undergraduate student. He joined the group in Fall 2021. He is working on fabrication of microfluidic platforms for cell and tissue cultures.
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Intracellular transport for mechanotransduction
A collaborative paper with Professor Sungsoo Na’s group at IUPUI is now published at Scientific Reports. Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling Qiaoqiao Wan, ThucNhi TruongVo, Hannah E. Steele, Altug Ozcelikkale, Bumsoo Han, Yingxiao Wang, Junghwan Oh , Hiroki Yokota & Sungsoo Na Abstract: Focal adhesion…
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Cover of WIREs Nanomedicine & Nanotechnology
Altug’s 3D drawing of nanoparticle transport through extracellular matrix from our recent article at WIREs Nanomedicine and Nanotechnology is selected as the Cover Image of the Issue.
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Michael Bradney, M.S.
Mike completed his M.S. study (2017) regarding pancreatic cancer model. He received Best Paper Award in 2017 ASME Summer Biomechanics, Bioengineering and Biotransport Conference. He moved to an Engineer position at Cook MED Institute. Check his latest activities at his Linkedin profile.
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Enzyme-Induced Matrix Softening
A collaborative paper with Professor Kong’s group at UIUC is now published at Macromolecular Bioscience. Enzyme-Induced Matrix Softening Regulates Hepatocarcinoma Cancer Cell Phenotypes Abstract The progression of cancer is often accompanied by changes in the mechanical properties of an extracellular matrix. However, limited efforts have been made to reproduce these biological events in vitro. To this…
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Mike Bradney’s MS Defense
Mike successfully completed his MSME defense. Development of an In Vitro Model for Pancreatic Ductal Adenocarcinoma Abstract Pancreatic ductal adenocarcinoma (PDAC) is a disease notorious for poor therapeutic response and low long-term survival. Despite its high fatality rate, there exists only one first line treatment option, on average extending life expectancy by less…