Author: btp.lab@gmail.com
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News Highlight at Big Ten Network
Our research on microfluidic tumor models are featured at Big Ten Network. Please read the article for details.
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Michael Linnes, Ph.D., Research Scientist
Michael is a research scientist in the Han Group. He received his Ph.D. in Bioengineering from the University of Washington (2009), and B.S. in Biomedical Engineering from the University of Minnesota (2003). His research interests are in tissue engineering and biomaterials. [ap_social facebook=”” twitter=”” gplus=”” linkedin=”https://www.linkedin.com/in/mlinnes/” dribble=””]
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Screening for effective chemotherapy
Our work to screen patient-specific drug efficacy using our microfluidic tumor platform is published in the Journal of Controlled Release. Differential response to doxorubicin in breast cancer subtypes simulated by a microfluidic tumor model Altug Ozcelikkale, Kyeonggon Shin, Victoria Noe-Kim, Bennett D.Elzey, Zizheng Dong, Jian-Ting Zhang, Kwangmeyung Kim, Ick Chan Kwon, Kinam Park, Bumsoo Han Abstract Successful drug delivery and overcoming drug resistance are the primary clinical challenges for management and treatment of…
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Biophysical models of chemotaxis
A collaborative paper with Professor Mugler’s group at Purdue Physics regarding collective and individual cell migrations induced by chemical gradient is published at Physical Review Letters. Emergent versus Individual-Based Multicellular Chemotaxis Julien Varennes, Sean Fancher, Bumsoo Han, and Andrew Mugler Abstract Multicellular chemotaxis can occur via individually chemotaxing cells that are mechanically coupled. Alternatively, it…
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Group 2017 at the Engineering Fountain
Stephanie, Bumsoo, Hye-Ran, Jingyi, Michael and Cih (right to left, after the group meeting of 10/23/2017)
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Video Clip: En Masse Migration of Fibroblasts
This videoclip shows the deformation of collagen matrix (left, bright fields) and migration of fibroblasts on the matrix (right, fluorescence micrographs). This videoclip illustrate that, when a large number of fibroblasts migrate all together (i.e., en masse), cells can collectively deform the matrices. Fibroblasts are seeded on the left half of each image. The matrix…
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Group migration of fibroblasts
Our work on massive migration of fibroblasts is published in the Journal of Royal Society Interface. Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices Altug Ozcelikkale, J. Craig Dutton, Frederick Grinnell, Bumsoo Han Abstract Fibroblast migration plays a key role during various physiological and pathological processes. Although migration of…
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ROS-responsive drug carrier
A collaborative paper with Professor Joon Kong’s group at UIUC is published at ASC Applied Materials & Interfaces. Active Antioxidizing Particles for On-Demand Pressure-Driven Molecular Release Yongbeom Seo, Jiayu Leong, Jye Yng Teo, Jennifer W. Mitchell, Martha U. Gillette, Bumsoo Han, Jonghwi Lee, and Hyunjoon Kong Abstract Overproduced reactive oxygen species (ROS) are closely…
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Altug Ozcelikkale, Ph.D., Postdoc Fellow
Altug completed his Ph.D. study in Mechanical Engineering at Purdue University (2015), and worked as a Postdoc Fellow (2017) in the Han Group. He moved to a Postdoc Fellow Position at the University of Maryland. Check his latest activities at his Linkedin Profile.
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Anuhya Edupuganti, Undergrad Student
Anuhya (Anu) graduated with B.S. in Mechanical Engineering Major at Purdue University in May 2022. She joined the Han Research Group in January 2020.
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Jessica Bendell, Undergraduate Student
Jessica is a undergraduate student with Biomedical Engineering Major. She joins the Han Research Group in August 2018.
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Samuel Schiavitti, Undergraduate Student
Sam graduated with B.S. in Mechanical Engineering at Purdue University in May 2022. He worked on design and manufacturing high throughput 3D cell culture platform by 3D printing.