Cell as a logic gate

Hye-ran’s paper on directed cell migration with Andrew Mugler’s group is published on the Journal Lab on a Chip. It is also selected as Lab on a Chip HOT Article 2023. In this work, Hye-ran proposed model migrating cancer cells as digital logic gates to process entangled chemical and fluidic microenvironmental cues. Cells function as …

Cell’s signal processing machinery

Hye-ran’s paper collaboratively developed with Dr. Mugler’s group at the University of Pittsburgh is now published in Journal iScience. We studied the cells’ biophysical capacity to decipher complex chemical cues during migration. Signal processing capacity of the cellular sensory machinery regulates the accuracy of chemotaxis under complex cues Hye-ran Moon, Soutick Saha, Andrew Mugler, and …