Cell adhesion and migration on nanopetal

PetalAdhsion_16_MatLet
A collaborative paper with Professor Tim Fisher's group on adhesion and migration of cells on graphitic nanopetal structures is published in Materials Letters. Guidance of cell adhesion and migration by graphitic nanopetals on carbon fibers Soham Ghosh, Guoping Xiong, Timothy S. Fisher and Bumsoo Han Abstract Carbon-based nanomaterials have emerged in a wide variety of applications because...
Read More

Simulation of Collective Chemotaxis

gr1
A collaborative paper with Professor Andrew Mugler's group in Physics is published in Biophysical Journal, and the result is highlighted at the Journal website (Video).   Collective Chemotaxis through Noisy Multicellular Gradient Sensing Julien Varennes, Bumsoo Han, Andrew Mugler Abstract Collective cell migration in response to a chemical cue occurs in many biological proces...
Read More

Review on tumor-microenvironment-on-chip

PDAC TME transport
A collaborative review on in vitro tumor models using microfluidics and tissue engineering is published in Cancer Letters. Recapitulation of complex transport and action of drugs at the tumor microenvironment using tumor-microenvironment-on-chip Bumsoo Han, Chunjing Qu, Kinam Park, Stephen F. Konieczny, Murray Korc Abstract: Targeted delivery aims to selectively distribute...
Read More

Cellular Pharmacokinetics using T-MOC

figure4A
Our work to characterize cellular pharmacokinetics (i.e., drug uptake) using tumor-microenvironment-on-chip and quantitative microscopy is published in Molecular Pharmaceutics.   Corresponding news release can also be found here.   Characterization of Cell-Type-Specific Drug Transport and Resistance of Breast Cancers Using Tumor-Microenvironment-on-Chip Kyeonggon Shin, Brett S. K...
Read More

Drug delivery using DNA walker

DNAWalker
A collaborative paper with Professor Jong Choi's group using DNA walker as a new drug delivery system is accepted for publication in the Journal ChemBioChem.     DNA Walker-Regulated Cancer Cell Growth Inhibition Feiran Li, Tae-Gon Cha, Jing Pan, Altug Ozcelikkale, Bumsoo Han, and Jong Hyun Choi Abstract: We use a DNAzyme-based walker system as a controlled oligonucleo...
Read More